【2012】
- Yokoyama, U., Ishiwata, R., Jin, M., Kato, Y., Suzuki, O., Jin, H., Ichikawa, Y., Kumagaya, S., Katayama, Y., Fujita, T., Okumura, S., Sato, M., Sugimoto, Y., Aoki, H., Suzuki, S., Masuda, M., Minamisawa, S., and Ishikawa, Y.. Inhibition of EP4 signaling attenuates aortic aneurysm formation. (2012) PLOS one. in press
- Nakagawa, N., Yuhki, K., Kawabe, J., Fujino, T., Takahata, O., Kabara, M., Abe, K., Kojima, F., Kashiwagi, H., Hasebe, N., Kikuchi, K., Sugimoto, Y., Narumiya, S., and Ushikubi, F. The prostaglandin E2-EP4 system inherent in the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice. (2012) Kidney Int. in press
- Kawahara, K. Suenobu, M., Yoshida, A., Koga, K., Hyodo, A., Ohtsuka, H., Kuniyasu, A., Tamamaki, N., Sugimoto, Y., and Nakayama, H. Intracerebral microinjection of interleukin-4/interleukin-13 reduces beta-amyloid accumulation in the ipsilateral side and improves cognitive deficits in young APP23 mice.(2012) Neuroscience. 207, 243-260.
- Hoshino T, Namba T, Takehara M, Murao N, Matsushima T, Sugimoto Y, Narumiya S, Suzuki T, Mizushima T. Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP(4) receptor. (2012) J. Neurochem. 120, 795-805.
- Takano, H., Furuta, K., Yamashita, K., Sakanaka, M., Itano, N., Gohda, E., Nakayama, K., Kimata, K., Sugimoto, Y., Ichikawa, A., and Tanaka, S. Restriction of mast cell proliferation through hyaluronan synthesis by co-cultured fibroblasts. (2012) Biol. Pharm. Bull. 35, 408-412.
【2011】
- Inazumi, T., Shirata, N., Morimoto, K., Takano, H., Segi-Nishida, E., and Sugimoto, Y. Prostaglandin E2-EP4 signaling suppresses adipocyte differentiation in mouse embryonic fibroblasts via an autocrine mechanism. (2011) J. Lipid Res. 52, 1500-1508
【2010】
- Tamba, S., Yodoi, R., Morimoto, K., Inazumi, T., Sukeno, M., Segi-Nishida, M., Okuno, Y., Tsujimoto, G., Narumiya, S., and Sugimoto, Y. Expression profiling of cumulus cells reveals functional changes during ovulation and central roles of prostaglandin EP2 receptor in cAMP signaling.(2010) Biochimie. 92, 665-675.
- Ichikawa, A., Sugimoto, Y., and Tanaka, S. Molecular biology of histidine decarboxylase and prostaglandin receptors.(2010) Proc. Jpn. Acad., Ser. B. 86, 848-866.
- Kusaka, M., Katoh-Fukui, y., Ogawa, H., Miyabayashi, K., Baba, T., Shima, Y., Sugiyama, N., Sugimoto, Y., Okuno, Y., Kodama, R., Izuka-Kogo, A., Senda, T., Sasaoka, T., Kitamura, K., Aizawa, S., and Morohashi, K. Abnormal epithelial cell polarity and ectopie epidermal growth factor receptor(EGFR) expression induced in Emx2 KO embryonic gonads.(2010) Endocrinology, 151, 5893-5904.
- Katoh, H., Hosono, K., Ito, Y., Suzuki, T., Ogawa, Y., Kubo, H., Kamata, H., Mishima, T., Tamaki, H., Sakagami, H., Sugimoto, Y., Narumiya, S., Watanabe, M., and Majima, M. COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems.(2010) Am. J. Pathol. 176, 1469-1483.
- Mizuguchi, S., Ohno, T., Hattori, Y., Ae, T., Minamino, T., Satoh, T., Arai, K., Saeki, T., Hayashi, I., Sugimoto, Y., Narumiya, S., Saigenji, K., and Majima, M. Role of Prostaglandin E2-EP1 Receptor Signaling in Regulation of Gastric Motot Activity and Emptying.(2010) Am. J. Physiol. Gastrointest. Liver Physiol., 299,G1078-G1086.
- Ueno, T., Suzuki, T., Oikawa, A., Hosono, K., Kosaka, Y., Amano, H., Kitasato, H., Toda, M., Hayashi, I., Kato, T., Ito, Y., Sugimoto, Y., Narumiya, S., Okamoto, H., and Majima, M. Recruited bone marrow cells expressing the EP3 prostaglandin E receptor subtype enhance angiogenesis during chronic inflammation. (2010) Biomed. Pharmacother. 64, 93-100.
- Kubo, H., Hosono, K., Suzuki, T., Ogawa, Y., Kato, H., Kamata, H., Ito, Y., Amano, H., Kato, T., Sakagami, H., Hayashi, I., Sugimoto, Y., Narumiya, S., Watanabe, M., and Majima, M. Host prostaglandin EP3 receptor signaling relevant to tumor-associated lymphangiogenesis.(2010) Biomed. Pharmacother. 64, 101-106.
【2009】
- Amano, H., Ito, Y., Suzuki, T., Kato, S., Matsui, Y., Ogawa, F., Murata, T., Sugimoto, Y., Senior, R., Kitasato, H., Hayashi, I., Satoh, Y., Narumiya, S., and Majima, M. Roles of a prostaglandin E-type receptor, EP3, in upregulation of matrix metalloproteinas e-9 and vascular endothelial growth factor during enhancement of tumor metastasis. (2009) Cancer. Sci. 100, 2318-2324.
- Kuge, Y., Obokata, N., Kimura, H., Katada, Y., Temma, T., Sugimoto, Y., Aita, K., Seki, K., Tamaki, N., and Saji, H. Synthesis and evaluation of a radioiodinated Lumiracoxib derivative for the imaging of cyclooxygenase-2 expression. (2009) Nuc. Med. Biol. 36, 869-876.
- Yamaoka, K., Yano, A., Kuroiwa, K., Morimoto, K., Inazumi, T., Hatae, N., Tabata, H., Segi-Nishida, E., Tanaka, S., Ichikawa, A., and Sugimoto, Y. Prostaglandin EP3 receptor superactivates adenylyl cyclase via the Gq/PLC/Ca2+ pathway in a lipid raft-dependent manner. (2009) Biochem. Biophys. Res. Commun. 389, 678-682.
- Suzuki-Yamamoto, T., Toida, K., Sugimoto, Y., and Ishimura, K. Colocalization of prostaglandin F receptor FP and prostglandin F synthase-I in the spinal cord. (2009) J. Lipid. Res. 50, 1996-2003.
- Yao, C., Sakata, D., Esaki, Y., Li, Y., Matsuoka, T., Kuroiwa, K., Sugimoto, Y., and Narumiya, S. Prostaglandin E2-EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion. (2009) Nat. Med. 15, 633-640.
- Yodoi, R., Tamba, S., Morimoto, K., Segi-Nishida, E., Nishihara, M., Ichikawa, A., Narumiya, S., and Sugimoto, Y. RhoA/Rho kinase signaling in the cumulus mediates extracellular matrix assembly. (2009) Endocrinology. 150, 3345-3352.
- Kunori, S., Matsumura, S., Mabuchi, T., Tatsumi, S., Sugimoto, Y., Minami, T., and Ito, S. Involvement of prostaglandin F2a receptor in ATP-induced mechanical allodynia. (2009 ) Neuroscience. 163, 362-371.
- Hoshino, T., Namba, T., Takehara, M., Nakaya, T., Sugimoto, Y., Araki, W., Narumiya, S., Suzuki, T., and Mizushima, T. Prostaglandin E2 stimulates the production of amyloid beta peptides through internalization of the EP4 receptor. (2009) J. Biol. Chem. 284, 18493-18502.
- Ogawa, Y., Suzuki, T., Oikawa, A., Hosono, K., Kubo, H., Amano, H., Kitasato, H., Hayashi, I., Kato, T., Sugimoto, Y., Narumiya, S., Watanabe, M., and Majima, M. Bone marrow-derived EP3-expressing stromal cells enhance tumor-associated angiogenesis and tumor growth. (2009) Biochem. Biophys. Res. Commun. 382, 720-725.
- Hori, R., Nakagawa, T., Sugimoto, Y., Sakamoto, T., Yamamoto, N., Hamaguchi, K., Ito, J. Prostaglandin E receptor subtype EP4 agonist protects cochleae against noise-induced trauma. (2009) Neuroscience. 160, 813-819.
- Takano, H., Nakazawa, S., Shirata, N., Tamba, S., Furuta, K., Tsuchiya, S., Morimoto, K, Itano, N., Irie, A., Ichikawa, A., Kimata, K., Nakayama, K., Sugimoto, Y., and Tanaka, S. Involvement of CD44 in mast cell proliferation during terminal differentiation. (2009) Lab. Invest. 89, 446-455.
- Tsuchiya, S., Tachida, Y., Segi-Nishida, E., Okuno, Y., Tamba, S., Tsujimoto, G., Tanaka, S., and Sugimoto, Y. Characterization of gene expression profiles fordifferent types of mast cells pooled from mouse stomach subregions by an RNA amplification method. (2009) BMC. Genomics. 10, 35.
【2008】
- Sakanaka, M., Tanaka, S.,Sugimoto, Y., and Ichikawa, A. Essential role of EP3 subtype in prostaglandin E2-induced adhesion of mouse cultured and peritoneal mast cells to the Arg-Gly-Asp-enriched matrix. (2008) Am.J.Physiol.Cell. Physiol.295, C1427-C1433.
- Tamba,
S., Yodoi, R., Segi-Nishida, E., Ichikawa, A., Narumiya, S., and
Sugimoto, Y. Timely interaction between prostaglandin and chemokine
signaling is a prerequisite for successful fertilization. (2008) Proc. Natl. Acad. Sci. USA. 105, 14539-14544.
- Yano,
Y., Yano, A., Oishi, S., Fujii, N., Sugimoto, Y., and Matsuzaki, K.
Coiled-coil tag-robe system for quick labeling of membrane receptors in
living cells.(2008) ACS .Chem. Biol. 3, 341-345.
- Yano,
Y., Shimbo, T., Sugimoto, Y., and Matsuzaki, K. Intracellular third
loop-C-terminal tail interaction in prostaglandin EP3β receptor. (2008)
Biochem. Biophys. Res. Commun. 371, 846-849.
- Takano,
H., Nakazawa, S., Okuno, Y., Shirata, N., Tsuchiya, S., Kainoh, T.,
Takamatsu, S., Furuta, K., Taketomi, Y., Naito, Y., Takematsu, H.,
Kozutsumi, Y., Tsujimoto, G., Murakami, M., Kudo, I., Ichikawa, A.,
Nakayama, K., Sugimoto, Y., and Tanaka, A. Establishment of the culture
model system that reflects the process of terminal differentiation of
connective tissue-type mast cells. (2008) FEBS. Lett. 582, 1444-1450.
- Tsuchiya,
H., Oka, T., Nakamura, K., Ichikawa, A., Saper, C. B., and Sugimoto, Y.
Prostaglandin E2 attenuates preoptic expression of GABAA receptors via
EP3 receptors. (2008 ) J. Biol. Chem. 283, 11064-11071.
- Yuhki,
K.I., Ushikubi, F., Naraba, H., Ueno, A., Kato, H., Kojima, F.,
Narumiya, S., Sugimoto, Y., Matsushita, M., and Oh-Ishi, S.
Prostaglandin I2 plays a key role in zymosan-induced mouse
pleurisy.(2008) J. Pharmacol. Exp. Ther. 325, 601-609.
- Esumi,
S., Wu, S-X., Yanagawa, Y., Obata, K., Sugimoto, Y., and Tamamaki, N.
Method for single-cell microarray analysis and application to
gene-expression profiling of GABAergic neuron progenitors. (2008) Neurosci. Res. 60, 439-451.
- Yellon,
S. M., Ebner, C. A., and Sugimoto, Y. Parturition and recruitment of
macrophages in cervix of mice lacking the prostaglandin F
receptor. (2008) Biol. Reprod. 78, 438-444.
- Kawamata,
M., Yoshida, M. Sugimoto, Y., Kimura, T., Tonomura, Y., Takayanagi, Y.,
Yanagisawa, T., and Nishimori, K. Infusion of oxytocin induces
successful delivery in prostanoid FP-receptor-deficient mice. (2008) Mol. Cell. Endocrinol. 283, 32-37.
【2007】
- Hoshino,
T., Nakaya, T., Homan, T., Tanaka, K., Sugimoto, Y., Araki, W., Narita,
M., Narumiya, S., Suzuki, T., and Mizushima, T. Involvement of
prostaglandin E2 in production of amyloid-peptides both in vitro and in
vivo. (2007) J. Biol. Chem. 282, 32676-32688.
- Suzuki-Yamamoto,
T., Sugimoto, Y, Ichikawa, A., and Ishimura, K.Co-localization of
prostaglandin F synthase, cyclooxygenase-1 and prostaglandin F receptor
in mouse Leydig cells. (2007) Histochem. Cell. Biol. 128(4),317-322.
- Taketomi, Y., Sunaga, K,. Tanaka, S., Nakamura, M., Arata, S., Okuda, T., Moon, T.C., Chang, H.W., Sugimoto, Y.,
Kokame, K., Miyata, T., Murakami, M., and Kudo, I.Impaired mast cell
maturation and degranulation and attenuated allergic responses in
ndrg1-deficient mice. (2007) J. Immunol. 178, 7042-7053.
- Furuta, K., Nakayama, K., Sugimoto, Y.,
Ichikawa, A., and Tanaka, S.Activation of histidine decarboxylase
through post-translational cleavage by caspase-9 in a mouse mastocytoma
P-815. (2007) J. Biol. Chem. 282 (18), 13438-13446.
- Sugimoto, Y., and Narumiya, S.Prostaglandin E receptors. (2007) J. Biol. Chem. 282 (16), 11613-11617.
- Kawamata, M., Tonomura, Y., Kimura, T., Sugimoto, Y.,
Yanagisawa, T., and Nishimori, K.Oxytocin-induced phasic and tonic
contractions are modulated by the contractile machinery rather than the
quantity of oxytocin receptor. (2007) Am. J. Physiol. Endocrinol. Metab. 292 (4), E992-E999.
【2006】
- Yokoyama,
U., Minamisawa, S., Hong, Q., Ghatak, S., Akaike, T., Segi-Nishida, E.,
Iwasaki, S., Iwamoto, M., Misra, S., Tamura, K., Hori, H., Yokota, S.,
Toole, B.P., Sugimoto, Y., and Ishikawa, Y.Chronic activation
of the prostaglandin receptor EP4 promotes hyaluronan-mediated
neointimal formation in the ductus arteriosus. (2006) J. Clin. Invest. 116, 3026-3034.
- Osada, S., Naganawa, A., Misonou, M., Tsuchiya. S., Tamba, S., Okuno, Y., Nishikawa, J., Satoh, K., Imagawa, I, Tsujimoto, G., Sugimoto, Y.,
and Nishihara, T.Altered gene expression of transcriptional regulatory
factors in tumor marker-positive cells during chemically induced
hepatocarcinogenesis. (2006) Toxicol. Lett. 167, 106-113.
- Trivedi, D.B., Sugimoto, Y., and Loftin, C.D.Attenuated cyclooxygenase-2 expression contributes to patent ductus arteriosus in preterm mice. (2006) Pediatr. Res. 60, 669-674.
- Shioji, M., Fukuda, H., Kanzaki, T., Wasada, K., Kanagawa, T., Shimoya, K., Mu, J., Sugimoto, Y.,
Murata, Y.Reduction of aquaporin-8 on fetal membranes under
oligohydramnios in mice lacking prostaglandin F2 alpha receptor. (2006)
J. Obstet. Gynaecol. Res. 32, 373-378.
- Kim, H., Arakawa, H., Hatae, N., Sugimoto, Y.,
Matsumoto, O., Osada, T., Ichikawa, A., and Ikai, A. Quantification of the
number of EP3 receptors on a living CHO cell surface by the AFM.(2006) Ultramicroscopy. 106, 652-662.
【2005】
- Liu, Y.,
Furuta, K., Teshima, R., Shirata, N., Sugimoto, Y., Ichikawa, A., and Tanaka,
S.Critical
role of PKC[beta]II in activation of mast cells by monomeric IgE. (2005) J. Biol. Chem. 280, 38976-38981.
- Shoji, Y., Takahashi, M., Takasuka, N., Niho, N., Kitamura, T., Sato, H.,
Maruyama, T., Sugimoto, Y., Narumiya, S., Sugimura, T. and Wakabayashi, K.Prostaglandin
E receptor EP3 deficiency modifies tumor outcome in mouse two-stage skin carcinogenesis. (2005)
Carcinogenesis. 12, 2116-2122.
- Sugimoto, Y., Fukada, Y., Mori,
D., Tanaka, S., Yamane, H., Okuno, Y., Deai, K., Tsuchiya, S., Tsujimoto,
G. and Ichikawa, A.Prostaglandin
E2 stimulates granulocyte colony-stimulating factor production via the prostanoid
EP2 receptor in mouse peritoneal neutrophils. (2005) J. Immunol. 175, 2606-2612.
- Takasaki, I., Nojima, H., Shiraki, K., Sugimoto,
Y., Ichikawa, A., Ushikubi, F., Narumiya, S. and Kuraishi, Y.Involvement
of cyclooxygenase-2 and EP(3) prostaglandin receptor in acute herpetic but
not postherpetic pain in mice. (2005)
Neuropharmacol. 49, 283-292.
- Kunikata,
T., Yamane, H., Segi, E., Matsuoka, T., Sugimoto, Y., Tanaka, S., Tanaka,
H., Nagai, H., Ichikawa, A. and Narumiya, S.Suppression
of allergic inflammation by the prostaglandin E receptor subtype EP3. (2005) Nat. Immunol. 6, 524-531.
- Moriyama, T., Higashi, T., Togashi, K., Iida, T., Segi, E., Sugimoto, Y.,
Tominaga, T., Narumiya, S. and Tominaga, M.Sensitization
of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins.
(2005) Mol. Pain.
1, 1-13.
- Foyouzi, N., Cai, Z.,
Sugimoto, Y. and Stocco, C.Changes in the expression of steroidogenic and antioxidant
genes in the mouse corpus luteum during luteolysis. (2005) Biol. Reprod. 72,1134-1141.
- Tanaka, S., Mikura, S., Hashimoto, E., Sugimoto, Y. and
Ichikawa, A.Ca2+
influx-mediated histamine synthesis and IL-6 release in mast cells activated
by monomeric IgE. (2005) Eur. J. Immunol. 35, 460-468.
-
Hirasawa, A., Tsumaya, K., Awaji, T., Katsuma, S., Adachi, T., Yamada,
M., Sugimoto, Y., Miyazaki, S. and Tsujimoto, G.Free fatty acids
regulate gut incretin glucagon-like peptide-1 secretion through GPR120.
(2005) Nature. Med. 11, 90-94.
【2004】
- Tsuboi, H., Sugimoto, Y., Kainoh, T. and Ichikawa, A.Prostanoid
EP4 receptor is involved in suppression of 3T3-L1 adipocyte differentiation. (2004) Biochem.
Biophys. Res. Commun. 322, 1066-1072.
- Sugimoto, Y., Tsuboi, H., Okuno, Y., Tamba, S.,
Tsuchiya, S., Tsujimoto, G. and Ichikawa, A.Microarray
evaluation of EP4 receptor-mediated prostaglandin E2 suppression of 3T3-L1
adipocyte differentiation. (2004) Biochem. Biophys.
Res. Commun. 322, 911-917.
- Shoji,
Y., Takahashi, M., Kitamura, T., Watanabe, K., Kawamori, T., Maruyama, T.,
Sugimoto, Y., Negishi, M., Narumiya, S., Sugimura, T. and Wakabayashi, K.Downregulation
of prostaglandin E receptor subtype EP3 during colon cancer development.
(2004) Gut. 53, 1151-1158.
- Tanaka, S., Deai, K., Konomi, A., Takahashi, K., Yamane, H., Sugimoto,
Y. and Ichikawa, A.Expression
of L-histidine decarboxylase in granules of elicited mouse polymorphonuclear
leukocytes. (2004) Eur. J. Immun. 34, 1472-1482.
- Sugimoto, Y., Nakato, T., Kita, A.,
Takahashi, Y., Hatae, N., Tabata, H., Tanaka, S. and Ichikawa, A.A
cluster of aromatic amino acids in the i2 loop plays a key role for Gs coupling
in prostaglandin EP2 and EP3 receptors. (2004) J.
Biol. Chem. 279, 11016-11026.
【2003】
- Oka, T., Oka, K., Kobayashi, T., Sugimoto, Y., Ichikawa,
A., Ushikubi, F., Narumiya, S. and Saper, CB.Characteristics
of thermoregulatory and febrile responses in mice deficient in prostaglandin
EP1 and EP3 receptors. (2003) J. Physiol. 551,
945-954.
- Sugimoto, Y., Nakato, T., Kita, A., Hatae, N., Tabata, H., Tanaka, S. and
Ichikawa, A.Functional
domains essential for Gs activity in prostaglandin EP2 and EP3 receptors.
(2003) Life. Sci. 74, 135-141.
- Tsuchiya, S., Tanaka, S.,
Sugimoto, Y., Katsuyama, M., Ikegami, R. and Ichikawa, A.Identification
and characterization of a novel progesterone receptor-binding element in the
mouse prostaglandin E receptor subtype EP2 gene. (2003) Genes.
to. Cells. 8, 747-758.
- Saito, O., Guan, Y., Qi,
Z., Davis, LS., Komhoff, M., Sugimoto, Y., Narumiya, S., Breyer, RM. and Breyer,
MD.Expression
of the prostaglandin F receptor (FP) gene along the mouse
genitourinary tract. (2003) Am. J. Physiol. Renal.Physiol. 284, F1164-1170.
- Minami, T., Matsumura, S., Mabuchi, T., Kobayashi, T.,
Sugimoto, Y., Ushikubi, F., Ichikawa, A., Narumiya, S. and Ito, S.Functional
evidence for interaction between prostaglandin EP3 and kappa-opioid receptor
pathways in tactile pain induced by human immunodeficiency virus type-1 (HIV-1)
glycoprotein gp120. (2003)
Neuropharmacol. 45, 96-105.
- Shoda, J., Ueda, T., Kawamoto, T., Todoroki,
T., Asano, T., Sugimoto, Y., Ichikawa, A., Maruyama, T., Nimura, Y., and Tanaka,
N.Prostaglandin
E receptors in bile ducts of hepatolithiasis patients and the pathobiological
significance for cholangitis. (2003) Clin. Gastroenterol. Hepatol. 1, 285-296.
- Tsuboi, K., Iwane, A., Nakazawa, S., Sugimoto, Y. and Ichikawa, A.Role
of prostaglandin H2 synthase 2 in murine parturition: study on ovariectomy-induced
parturition in prostaglandin F receptor-deficient
mice. (2003)
) Biol.Reprod. 69, 195-201.
- Hatae, N., Kita, A., Tanaka,
S., Sugimoto, Y. and Ichikawa, A.Induction
of adherent activity in mastocytoma P-815 cells by the cooperation of two
prostaglandin E2 receptor subtypes, EP3 and EP4.(2003) J. Biol. Chem. 278, 17977-17981.
- Mu, J., Kanzaki, T., Si, X., Tomimatsu, T., Fukuda,
H., Shioji, M., Murata, Y., Sugimoto, Y. and Ichikawa, A.Apoptosis
and related proteins in placenta of intrauterine fetal death in prostaglandin
F receptor-deficient mice. (2003) Biol.Reprod. 68, 1968-1974.
- Segi, E., Haraguchi, K., Sugimoto, Y., Tsuji, M., Tsunekawa, H., Tamba, S.,
Tsuboi, K., Tanaka, S. and Ichikawa, A.Expression
of messenger RNA for prostaglandin E receptor subtypes EP4/EP2 and cyclooxygenase
isozymes in mouse periovulatory follicles and oviducts during superovulation. (2003) Biol.Reprod. 68, 804-811.
- Amano, H., Hayashi, I., Endo, H., Kitasato, H., Yamashina, S.,
Maruyama, T., Kobayashi, M., Satoh, K., Narita, M., Sugimoto, Y., Murata,
T., Yoshimura, H., Narumiya, S. and Majima, M.Host
prostaglandin E(2)-EP3 signaling regulates tumor-associated angiogenesis and
tumor growth. (2003) J. Exp. Med.
197, 221-232.
【2002】
- Tsuboi, K., Sugimoto, Y. and Ichikawa, A.Prostaglandin E2 and F2 alpha
in mouse reproduction. (2002) International
Congress Series, 3rd International Conference on Oxygen and Life (Ishimura,
Y., ed.), 1233, 397-404.
- Tsuboi, K., Sugimoto, Y. and Ichikawa, A.Prostanoid
receptor subtypes. (2002) Prostaglandins
& other Lipid Mediators, 68-69, 535-556.
- Tsuboi, K., Segi, E., Sugimoto,
Y. and Ichikawa, A.Role of prostanoids on female
reproduction revealed by receptor-deficient mice. (2002) Recent Res. Devel. Endocrinol.,
3, 119-126.
- Tabata, H., Tanaka, S., Sugimoto, Y., Kanki, H., Kaneko,
S. and Ichikawa, A.Possible
coupling of prostaglandin E receptor EP1 to TRP5 expressed in Xenopus
laevis oocytes. (2002) Biochem. Biophys. Res. Commun.,
298, 398-402.
- Asano,
T., Shoda, J., Ueda, T., Kawamoto, T., Todoroki, T., Shimonishi, M., Tanabe,
T., Sugimoto, Y., Ichikawa, A., Mutoh, M., Tanaka, N. and Miwa, M.Expressions
of cyclooxygenase-2 and prostaglandin E-receptors in carcinoma of the gallbladder:
crucial role of arachidonate metabolism in tumor growth and progression. (2002)
Clin. Cancer Res., 8, 1157-1167.
- Mu,J.,Kanzaki,t.,Tomimatsu,T.,Fukuda,H.,Wasada,K.,Fujii,E.,Endoh,M.,Kozuki,M.,Murata,Y.,Sugimoto,Y.,and Ichikawa,A.Expression
of apoptosis in placentae from mice lacking the prostaglandin F receptor.(2002) Placenta,
23, 215-223.
- Hatae, N., Sugimoto,
Y. and Ichikawa, A.Prostaglandin
receptors: Advances in the study of EP3 receptors signaling. (2002) J. Biochem. 131, 781-784.
- Safina,F.,Tanaka,S.,Inagaki,M.,Tuboi,K.,Sugimoto,Y.,and Ichilawa,A.,Expression
of L-histidine decarboxylase in mouse male germ cells. (2002) J.
Biol. Chem. 277, 14211-14215.
- Kabashima,K.,Murata,T.,Nagamachi,M.,Matsuoka,T.,Segi,E.,Tsuboi,K.,Sugimoto,Y.,Kobayashi,T.,Miyachi,Y.,Ichikawa,A.,and
Narumiya,S.The prostaglandin receptor EP4 suppresses colitis, mucosal
damage and CD4 cell activation in the gut.(2002) J. Clin. Invest.. 109, 883-893.
- Yoshida,K.,Oida,H.,Kobayashi,T.,Maruyama,T.,Tanaka,M.,Katayama,T.,Yamaguchi,K.,Segi,E.,Tsuboyama,T.,Matsushita,M.,Ito,K.,Ito,Y.,Sugimoto,Y.,Ushikubi,F.,Ohuchida,S.,Kondo,K.,Nakamura,T.and
Narumiya,S.Stimulation of bone formation and prevention of bone loss by
prostaglandin E EP4 receptor activation. (2002) Proc. Natl. Acad. Sci. USA. 99,
4580-4585.
- Mu,J.,Kanzaki,T.,Si,X.,Tomimatsu,T.,Fukuda,H.,Fujii,E.,Hosono,T.,Murata,Y.,Sugimoto,Y.and Ichikawa,A.Apoptosis
and related proteins during parturition in prostaglandin F receptor-deficient
mice. (2002) Biochem. Biophys.
Res. Commun., 292, 675-681.
- Fennekohl,A.,Sugimoto,Y.,Segi,E.,Maruyama,T.,Ichikawa,A.and Puschel,G.P.Contribution
of the two Gs-coupled PGE2-receptors EP2-receptor and EP4-receptor to the
inhibition by PGE2 of the LPS-induced TNF alpha -formation in Kupffer cells
from EP2-or EP4-receptor-deficient mice. Pivotal role for the EP4-receptor
in wild type Kupffer cells. (2002) J. Hepatol. 36,
328-334.
- Mutoh,M.,Watanabe,K.,Kitamura,T.,Shoji,Y.,Takahashi,M.,Kawamori,T.,Tani,K.,Kobayashi,M.,Maruyama,T.,Kobayashi,K.,Ohuchida,S.,Sugimoto,Y.,Narumiya,S.,Sugimura,T.and
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